Articles Accessed Most Frequently

These are the Top 20 Papers (by download) for the 30 days preceding May 8, 2008. You can see the summaries if you are registered, or full text and PDFs if you have subscribed.

1.  Opposing Effects of Dietary Protein and Sugar Regulate a Transcriptional Target of Drosophila Insulin-like Peptide Signaling
Susanne Buch, Christoph Melcher, Matthias Bauer, Joerg Katzenberger and Michael J. Pankratz
[Summary]  [Fulltext]  [PDF] 
Apr 09, 2008 
7 (4)
2.  Transcriptional Regulation of Adipogenesis by KLF4
K?vanç Birsoy, Zhu Chen and Jeffrey Friedman
[Summary]  [Fulltext]  [PDF] 
Apr 09, 2008 
7 (4)
3.  PDK1 Deficiency in POMC-Expressing Cells Reveals FOXO1-Dependent and -Independent Pathways in Control of Energy Homeostasis and Stress Response
Bengt F. Belgardt, Andreas Husch, Eva Rother, Marianne B. Ernst, F. Thomas Wunderlich, Brigitte Hampel, Tim Klöckener, Dario Alessi, Peter Kloppenburg and Jens C. Brüning
[Summary]  [Fulltext]  [PDF] 
Apr 09, 2008 
7 (4)
4.  Mice with Mitochondrial Complex I Deficiency Develop a Fatal Encephalomyopathy
Shane E. Kruse, William C. Watt, David J. Marcinek, Raj P. Kapur, Kenneth A. Schenkman and Richard D. Palmiter
[Summary]  [Fulltext]  [PDF] 
Apr 09, 2008 
7 (4)
5.  Hepatic Steatosis in Leptin-Deficient Mice Is Promoted by the PPARγ Target Gene Fsp27
Kimihiko Matsusue, Takashi Kusakabe, Takahiro Noguchi, Shouichi Takiguchi, Toshimitsu Suzuki, Shigeru Yamano and Frank J. Gonzalez
[Summary]  [Fulltext]  [PDF] 
Apr 09, 2008 
7 (4)
6.  Hypothalamic CaMKK2 Contributes to the Regulation of Energy Balance
Kristin A. Anderson, Thomas J. Ribar, Fumin Lin, Pamela K. Noeldner, Michelle F. Green, Michael J. Muehlbauer, Lee A. Witters, Bruce E. Kemp and Anthony R. Means
[Summary]  [Fulltext]  [PDF] 
May 07, 2008 
7 (5)
7.  Complex I: A Complex Gateway to the Powerhouse
Fredrik Hansson Sterky and Nils-Göran Larsson
[Summary]  [Fulltext]  [PDF] 
Apr 09, 2008 
7 (4)
8.  The GLUT4 Glucose Transporter
Shaohui Huang and Michael P. Czech
[Summary]  [Fulltext]  [PDF] 
Apr 04, 2007 
5 (4)
9.  Rapid Activation of Akt2 Is Sufficient to Stimulate GLUT4 Translocation in 3T3-L1 Adipocytes
Yvonne Ng, Georg Ramm, Jamie A. Lopez and David E. James
[Summary]  [Fulltext]  [PDF] 
Apr 09, 2008 
7 (4)
10.  Fly-let Biology and the High Protein/Low Carb Diet
Eric Rulifson
[Summary]  [Fulltext]  [PDF] 
Apr 09, 2008 
7 (4)
11.  Hepatic Fibroblast Growth Factor 21 Is Regulated by PPARα and Is a Key Mediator of Hepatic Lipid Metabolism in Ketotic States
Michael K. Badman, Pavlos Pissios, Adam R. Kennedy, George Koukos, Jeffrey S. Flier and Eleftheria Maratos-Flier
[Summary]  [Fulltext]  [PDF] 
Jun 06, 2007 
5 (6)
12.  Glucose Restriction Extends Caenorhabditis elegans Life Span by Inducing Mitochondrial Respiration and Increasing Oxidative Stress
Tim J. Schulz, Kim Zarse, Anja Voigt, Nadine Urban, Marc Birringer and Michael Ristow
[Summary]  [Fulltext]  [PDF] 
Oct 03, 2007 
6 (4)
13.  Iron Homeostasis: Fitting the Puzzle Pieces Together
Tomas Ganz
[Summary]  [Fulltext]  [PDF] 
Apr 09, 2008 
7 (4)
14.  Drosophila ALS Regulates Growth and Metabolism through Functional Interaction with Insulin-Like Peptides
Nathalie Arquier, Charles Géminard, Marc Bourouis, Gisèle Jarretou, Basil Honegger, Alexandre Paix and Pierre Léopold
[Summary]  [Fulltext]  [PDF] 
Apr 09, 2008 
7 (4)
15.  When BAD Is Good for β Cells
Louis H. Philipson and Michael W. Roe
[Summary]  [Fulltext]  [PDF] 
Apr 09, 2008 
7 (4)
16.  Reduced TOR Signaling Extends Chronological Life Span via Increased Respiration and Upregulation of Mitochondrial Gene Expression
Nicholas D. Bonawitz, Marc Chatenay-Lapointe, Yong Pan and Gerald S. Shadel
[Summary]  [Fulltext]  [PDF] 
Apr 04, 2007 
5 (4)
17.  Bruton and Tec: New Links in Osteoimmunology
Brendan F. Boyce and Lianping Xing
[Summary]  [Fulltext]  [PDF] 
Apr 09, 2008 
7 (4)
18.  Diabetes and Cognitive Decline: Are Steroids the Missing Link?
Alasdair M.J. MacLullich and Jonathan R. Seckl
[Summary]  [Fulltext]  [PDF] 
Apr 09, 2008 
7 (4)
19.  Fast/Glycolytic Muscle Fiber Growth Reduces Fat Mass and Improves Metabolic Parameters in Obese Mice
Yasuhiro Izumiya, Teresa Hopkins, Carl Morris, Kaori Sato, Ling Zeng, Jason Viereck, James A. Hamilton, Noriyuki Ouchi, Nathan K. LeBrasseur and Kenneth Walsh
[Summary]  [Fulltext]  [PDF] 
Feb 06, 2008 
7 (2)
20.  SIRT1 Improves Insulin Sensitivity under Insulin-Resistant Conditions by Repressing PTP1B
Cheng Sun, Fang Zhang, Xinjian Ge, Tingting Yan, Xingmiao Chen, Xianglin Shi and Qiwei Zhai
[Summary]  [Fulltext]  [PDF] 
Oct 03, 2007 
6 (4)